I saw something similar to this awhile back and thought "how can that be. It's only my hands using it." Anyway, I wipe mine with a towelet such as WetOnes occasionally and wipe the mouse well, too. I know this really doesn't do much, but it's something. Thanks for the reminder. We tend to think we're clean when in reality we live in a very dirty world and while a little dirt is good for you, some dirt and too much is not.