As a Pest Mgmt. Professional, I have dealt with bed bugs many times. The product I use most is Bedlam Plus which comes in an aerosol can. It helps to vacuum everything in site at the start, then place the vacuum bag in a plastic bag, tie it, and dispose of it outside. Lots of websites can help you through the procedure; but, when the house gets greatly infested, it's best to call in a professional with a heat system. Tent fumigation is also widely used to kill bed bugs.