I think my favorite line(s) from the film is/are:
Ted: "I've flown single engine planes in the war...a long time ago. But this has four engines! It's an entirely different kind of flying, all together."
Dr. Rumack and stewardess (in unison): "It's an entirely different kind of flying."
It took me a few seconds to catch on what they were doing, but then I couldn't stop laughing! Too good! Or else there's this one...
Stewardess: "Excuse me sir, there's been a problem in the cockpit and..."
Ted (interrupting): "The cockpit! What is it?"
Stewardess: "It's a small room at the front of the plane where the pilot sits, but that's not important right now."